Orlistat Capsule

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Therapeutic Indication

Obesity management
Weight loss (with low-calorie diet)
Overweight patients with risk factors (e.g., diabetes, hypertension)
Long-term weight maintenance
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Orlistat

Capsule

Orlistat is a lipase inhibitor used for weight management. It works by reducing the absorption of dietary fats in the intestine, thereby decreasing calorie intake and promoting weight loss. It is most effective when used along with a calorie-controlled diet and lifestyle modifications.

Speciality Endocrinology
Tags Anti-obesity | Lipase Inhibitor | Weight Loss
Strength
  • 60 mg
  • 120 mg
Packing Size
  • 10 Capsules

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Mechanism

Orlistat inhibits gastric and pancreatic lipases, enzymes responsible for breaking down triglycerides in the intestine. This prevents the absorption of approximately 25–30% of dietary fat, which is then excreted undigested in the feces.

Side Effects

  • Oily stools
  • Flatulence with discharge
  • Frequent bowel movements
  • Abdominal discomfort

Dosage

  • As directed by the physician

Contraindication

  • Hypersensitivity to Orlistat or any component of the formulation
  • Pregnancy
  • Breastfeeding (lactation)
  • Chronic malabsorption syndrome
  • Cholestasis (reduced or blocked bile flow)

Interaction

  • Cyclosporine:Reduced absorption
  • WarfarinAltered anticoagulant effect (due to vitamin K deficiency)
  • Fat-soluble vitamins :Reduced absorption (A, D, E, K)
  • Antidiabetic drugs:May enhance glucose control

Warning and Precautions

This has been prescribed for the patient's specific condition. It may be dangerous to any other person.

  • Follow a low-fat diet to minimize side effects
  • Take multivitamin supplements (at least 2 hours after dose)
  • Monitor liver function in long-term use
  • Avoid excessive fat intake (increases GI side effects)
  • Use cautiously in patients with kidney stones
  • Not recommended during pregnancy and lactation

Disclaimer

All product details on this website are for reference and informational purposes only and are not directed at patients or consumers.
As a contract manufacturer, DM Pharma Pvt Ltd is not responsible for the marketing or end use of these products and disclaims all liability arising from reliance on this information.
Please consult a healthcare professional before using any medicinal product.